She took a leave of absence to explore non-western wellness practices, and in addition to significant lifestyle changes, she developed a meditation practice. Smalley was diagnosed with an early stage melanoma in 2002. She wrote extensively on the strengths of those with ADHD, characterizing it as a different way of thinking rather than a deficit.
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Her lab produced more than 40 publications on the disorder, including the first genome-wide scan (in conjunction with investigators at Oxford University), candidate gene investigations, and a series of papers on ADHD among a northern Finnish birth cohort. Smalley's focus subsequently shifted to ADHD. She continued to research autism for the following ten years, producing numerous papers on the genetics and subclinical variants of autism beyond the diagnostic classification as well as genetic and behavioral studies of TSC.
Following its publication, she received a National Institute of Health (NIH) grant to investigate genetic determinants in autism, and pioneered an approach to behavioral genetics by studying known genetic disorders with behavioral sequelae, specifically, the study of tuberous sclerosis complex, (TSC), a genetic disorder in which autistic disorder occurs at higher rates than the general population. In 1988 she published a review paper on the genetics of autism in JAMA Psychiatry.
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Smalley joined the faculty at UCLA after she completed post-doctoral fellowships in medical genetics and childhood psychopathology, moving from assistant to full professor until her retirement to emeritus in 2011. Smalley is also on the scientific advisory board for Stop Breathe and Think, an app for emotional well being and the board of directors for Equality Now, an international human rights organization focused on women and girls and was honored by Equality Now in December 2019. In 2010, she co-founded Cell-Ed, a platform to bring basic literacy to adults in underserved populations using mobile phones. Smalley is on the board of directors for Roswell Biotechnologies, a molecular electronics company that developed a molecular electronics chip to read DNA and a novel system approach to reduce whole genome sequencing, each to provide precision medical treatment. PTK Capital supports "people and ideas with the potential to significantly benefit the human condition." The firm's investment activities focus on transformative companies in the areas of Entertainment, Food and Wellness. Smalley is the co-founder of PTK Capital, an investment fund that invests in early stage companies and venture capital funds. She has published more than 100 peer-reviewed papers and lectured globally on the genetics of human behavior and the science of mindfulness. Her research centers on the genetic basis of childhood-onset behavior disorders, such as ADHD, and the cognitive and emotional impact of mindfulness meditation on health and wellbeing. The co-author of Fully Present: The Science, Art, and Practice of Mindfulness, she is the founder of the UCLA Mindful Awareness Research Center at the Jane and Terry Semel Institute for Neuroscience and Human Behavior (MARC), and professor emerita in the department of psychiatry and biobehavioral sciences at UCLA. Susan Smalley is an American behavioral geneticist, writer and activist. Genetic influences on spatial ability: Transmission in an extended kindred (1985) Genetics of attention deficit hyperactivity Disorder (ADHD) and autism spectrum disorders University of California, Ph.D, Anthropology, 1985īehavioral Geneticist, Writer, Activist, Investor
University of California, Los Angeles, MA, Anthropology, 1981
University of Michigan, BA, Anthropology, 1976
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